East London Genes and Health
ELGH as a long-term resource for population genomic medicine research in British South Asians, delivering high quality basic science, translational, clinical and population health research. Areas of health importance identified by the local East London community are prioritised, including type 2 diabetes, cardiovascular disease and mental health. In addition to a health-deprived community, ELGH has a unique combination of features: high rates of consanguinity such that rare genetic variants occur as homozygotes, including homozygous predicted loss of function genotypes (knockouts); local excellence in e–health record access & analysis (enhanced by a new Health Data Research UK – London site); recall for further research by genotype and/or phenotype to excellent London clinical research facilities; and understudied (yet highly engaged) minority ethnic groups.
Data Sharing Potential