Linking cohorts, understanding biology, improving health

International HundredK+ Cohorts Consortium (IHCC)

Davos Alzheimer's Collaborative and IHCC Announce Milestones in the Fight Against Alzheimer’s Disease

The Davos Alzheimer’s Collaborative (DAC) is a global multi-stakeholder partnership that is mobilizing the world against Alzheimer’s disease, and the IHCC is proud to be a part of this million person cohort.

       “Now is the time to act on Alzheimer’s. International bodies including the WHO, G7, and G20 have all made commitments in recent years that recognize the need to act together, act globally and act now to address this health crisis…DAC is a response to these calls for action, bringing the speed and scale that has too often been lacking in previous efforts. The COVID-19 pandemic has shown us that a broad coalition of stakeholders working together can mobilize quickly to address a looming public health catastrophe.

                                                                                                                –George Vradenburg, Chair of DAC

In the first six months of operations, DAC linked 12 cohorts spanning Africa, Asia and South America, with more than 20 additional cohorts under consideration. DAC has also Stress-tested the combined cohort using the Polygenic Risk Score (PRS) Feasibility Pilot, a first-of-its-kind, transethnic and transracial analysis of genetic data from approximately 100,000 people with Alzheimer’s.    

IHCC will continue to support this combine by providing high-quality, detailed data on diverse populations. We will also include populations from low- and middle-income countries to increase the heterogeneity of the populations under study, and it will be paired with a gold standard cohort to create understanding of the ideal cohort sample composition. 

Read DAC’s official press release below for more information on this incredible initiative.